From John Belushi to Kate McKinnon, the “SNL” stars who inspired “The Midnight Show” cast (exclusive)

Co-authors Lee Kelly and Jennifer Thorne break down the comedy ions who helped inspire the ensemble cast of their new novel ...

The 50 best movies on HBO Max for dedicated cinephiles

Almost 100 years of cinema are represented on this list: starting with City Lights (1931) and extending all the way to 2026 ...

Marathon players see different colored lobsters and Bungie won’t explain why

Polygon spoke with Marathon developers about its color-changing lobsters, but Bungie still won’t explain the strange in-game ...

The 34 best dark comedies of all time

Dark times call for dark comedies. These 34 films look at life's bleaker moments and shine a light on the funny parts.
eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Beyond the Focus of Expansion: Retinal curl as a functional signal for heading estimation

This study provides an important and biologically plausible account of how human perceptual judgments of heading direction are influenced by a specific pattern of motion in optic flow fields known as ...
AHA/ASA Journals

Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...